Detalhe da pesquisa
1.
Dysfunctional mitochondrial translation and combined oxidative phosphorylation deficiency in a mouse model of hepatoencephalopathy due to Gfm1 mutations.
FASEB J
; 36(1): e22091, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34919756
2.
Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE): Position paper on diagnosis, prognosis, and treatment by the MNGIE International Network.
J Inherit Metab Dis
; 44(2): 376-387, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32898308
3.
Therapy Prospects for Mitochondrial DNA Maintenance Disorders.
Int J Mol Sci
; 22(12)2021 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34208592
4.
Deoxynucleoside Therapy for Thymidine Kinase 2-Deficient Myopathy.
Ann Neurol
; 86(2): 293-303, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31125140
5.
Increased dNTP pools rescue mtDNA depletion in human POLG-deficient fibroblasts.
FASEB J
; 33(6): 7168-7179, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30848931
6.
The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells.
PLoS Pathog
; 12(8): e1005829, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27541004
7.
Polyphosphate is involved in cell cycle progression and genomic stability in Saccharomyces cerevisiae.
Mol Microbiol
; 101(3): 367-80, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27072996
8.
Administration of deoxyribonucleosides or inhibition of their catabolism as a pharmacological approach for mitochondrial DNA depletion syndrome.
Hum Mol Genet
; 23(9): 2459-67, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24362886
9.
Inhibition of herpes simplex virus type 1 by the CDK6 inhibitor PD-0332991 (palbociclib) through the control of SAMHD1.
J Antimicrob Chemother
; 71(2): 387-94, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26542306
10.
Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells.
J Immunol
; 193(4): 1988-97, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25015816
11.
Gene therapy using a liver-targeted AAV vector restores nucleoside and nucleotide homeostasis in a murine model of MNGIE.
Mol Ther
; 22(5): 901-7, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24448160
12.
SAMHD1 specifically affects the antiviral potency of thymidine analog HIV reverse transcriptase inhibitors.
Antimicrob Agents Chemother
; 58(8): 4804-13, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24913159
13.
Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans.
Am J Physiol Gastrointest Liver Physiol
; 307(7): G673-88, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24970780
14.
Limited dCTP availability accounts for mitochondrial DNA depletion in mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).
PLoS Genet
; 7(3): e1002035, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21483760
15.
Effect of Resveratrol Content in Red Wine on Circulating Sex Hormone-Binding Globulin: Lessons from a Pilot Clinical Trial.
Mol Nutr Food Res
; 66(16): e2200125, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35751841
16.
Most mitochondrial dGTP is tightly bound to respiratory complex I through the NDUFA10 subunit.
Commun Biol
; 5(1): 620, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35739187
17.
RRM1 variants cause a mitochondrial DNA maintenance disorder via impaired de novo nucleotide synthesis.
J Clin Invest
; 132(13)2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35617047
18.
A novel nonstop mutation in TYMP does not induce nonstop mRNA decay in a MNGIE patient with severe neuropathy.
Hum Mutat
; 32(4): E2061-8, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21412940
19.
Yeast Ppz1 protein phosphatase toxicity involves the alteration of multiple cellular targets.
Sci Rep
; 10(1): 15613, 2020 09 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32973189
20.
Efficacy of adeno-associated virus gene therapy in a MNGIE murine model enhanced by chronic exposure to nucleosides.
EBioMedicine
; 62: 103133, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33232869